Session

Description


Applications of artificial intelligence and machine learning in biomechanics

Chair: Ferris M. Pfeiffer, University of Missouri, USA

Modeling, simulation, and big data analysis in biomechanics is becoming increasingly important. This session will explore the use of artificial intelligence and machine learning techniques to solve complex biomechanics problems.

Art & reproducibility in modeling and simulation

Chair: Ahmet Erdemir, Lerner Research Institute,

Cleveland Clinic, USA

 

 

 

This session will unveil potentially subjective decision making processes, the "art", of modelers when building virtual knees from the same data. Strategies, which may enhance reproducibility in computational biomechanics, will be highlighted. Participation is open for broad discussions in related topics that leverage examples not necessarily restricted to the knee but also from other biomechanical domains.

For details of the project on art & reproducibility in knee joint modeling, please refer to https://simtk.org/projects/kneehub 

Biomechanics of morphogenesis

Chair: Nandan Nerurkar, Columbia university, United States

 

 

 

This session will highlight recent advances in the application of engineering approaches to understand and manipulate emergent patterns in biological systems, with a particular focus on embryonic development. 

Biomechanics of tendons and ligaments

Chair: Mark R. Buckley, University of Rochester, USA

This session will broadly focus on computer methods applied to the study of tendon and ligament biomechanics. Talks will address topics ranging from tendon ultrasound elastography to computational models of tendons and ligaments. This session will be highlighted by a keynote presentation from Dr. Ellen Arruda (University of Michigan) and invited talks by Dr. Kristin Miller (Tulane University) and Dr. Michael Richards (Rochester Institute of Technology).

Brain biomechanics

Chairs: Aaron Feng, Shanghai Jiao Tong University, Schanghai

Songbai Ji, Worcester Polytechnic Institute, USA

This session will provide a forum for top researchers in the field to discuss latest findings regarding the biomechanics of the brain. Topics will focus on in vivo and ex vivo measurements of brain biomechanics as well as computational simulation strategies for topics on brain injury, neural development, brain tumor, and other neurological diseases or disorders. 

Calcific Aortic Valve Disease, bicuspid aortic valve and transcatheter aortic valve replacement

Chairs: Gil Marom, Tel Aviv University, Israel

Rami Haj-Ali, Tel Aviv University, Israel

This session deals with biomechanical and mechano-biology aspects of calcific aortic valve disease (CAVD), including in bicuspid aortic valve (BAV), and their treatment by transcatheter aortic valve replacement (TAVR). The session is open for talks on computational models of tissue (structure mechanics), hemodynamics (fluid dynamics) and their fluid structure interaction (FSI). Possible topics include, but are not limited to, mechano-biology and material models of the disease in CAVD and BAV, the hemodynamics of these diseases, and the TAVR treatment and its complications.

Cardiac mechanics I - Heart valve mechanics

Chairs: Joao Soares,  Mechanical and Nuclear Engineering, College of Engineering, USA

Daniel Hurtado, Pontificia Universidad Católica de Chile, Chile

Over the past decade, computational modeling in cardiac mechanics has been a powerful tool to understand and predict the behavior of the heart, its components, and their function in health and disease. These sessions bring together internationally-recognized experts to discuss different aspects of cardiac mechanics, including blood flow dynamics, myocardium mechanics, heart valve mechanics, fluid-structure interaction, cardiac electrophysiology, and cardiac morphogenesis, growth, adaptation, and remodeling. We have contributed talks on image-based computational modeling of myocardium function and heart valves, multi-scale methods of chemo-electro-mechanics, disease-specific modeling, and state-of-the-art methods for in vivo, in vitro, and in silico testing and characterization of the heart and its structures.

Cardiovascular fluid dynamics: patient-specific modeling

Chair: Lucas H. Timmins, University of Utah, USA

Recent advances in medical imaging and computational modeling techniques now provide the necessary tools to construct patient-specific models to predict the hemodynamic environment across numerous vascular territories. This session will highlight progress made to integrate patient-specific geometries and in vivo hemodynamics measures to elucidate the role of fluid mechanics in cardiovascular pathologies and how modeling efforts can be translated to the clinic to guide patient management. 

Computational methods in the design and evaluation of orthopaedic implant systems 

Chair: Heath Henninger, The University of Utah, USA

Computational methods have allowed exploration of the nuances of orthopaedic implant system design, hardware selection, component placement, and the interactions of these factors.  This session will highlight current techniques used in optimizing the application of orthopaedic implants and their relationship to human anatomy and movement.  

Computational modelling and 3D printing in tissue engineering

Chairs: Paulo Fernandes, University of Lisbon, Portugal

André Castro, University of Lisbon, Portugal

Tissue Engineering is a multidisciplinary field that combines efforts from biology, engineering and material science methods towards the development of biological substitutes to restore, maintain, or improve tissue functions. Computational methods for tissue engineering have been developed to study diverse tissue engineering issues. For this special session, submissions are invited on computer models to analyze and design scaffolds, to assist in the fabrication of new scaffolds and tissues, to understand the inter-relationships between scaffolds and cell attachment, proliferation and differentiation and to describe the tissue regeneration process and vascularization. 

Computational Modelling for Spine Biomechanics

Chairs: Giovanni Solitro, Louisiana State University Health Science Center-Shreveport, United States

Francesco Travascio, University of Miami, United States

In this session, top researchers in the field will present and discuss their outstanding findings regarding computational spine biomechanics.

Topics of the talks will focus on mechanics of fracture, osteoporosis, and surgical treatments for trauma and degenerative diseases.

Computational modeling in chemo-electro-mechanics of the heart

Chair: Joao Soares, Mechanical and Nuclear Engineering

College of Engineering, Virginia, USA

Dental biomechanics

Chairs: Jing Du, Penn State University, USA

Christoph Bourael, University of Bonn, Germany

This session broadly focuses on biomechanical investigations as related to dental research and dentistry, including dental implants,  orthodontics, and natural tooth mechanics. It covers a significant field of research within engineering and biomedicine in general. The session will encompass the following topics: Hard and soft tissue mechanics; Mechanical behaviors of dental materials, including alloys, polymer and ceramics; Computer methods on dental biomechanics; Imaging and image processing for dental research and clinical practice.

Development and application of soft tissue damage criteria

Chair: Corinne Henak, University of Wisconsin-Madison, USA

This session will highlight approaches to modeling damage in soft tissue.  Particular emphasis will be placed on experimental methods used to develop damage criteria.

Elastography imaging

Chair: Daniel H. Cortes, Pennsylvania State University, USA

The Elastography Session will present recent advances in imaging techniques designed to measure mechanical properties from soft tissues and applications to the diagnosis and evaluation of different diseases and pathological conditions. 

Growth and remodelling in reproductive biomechanics

Chair: Kristin Miller, Tulane University, USA

This session is intended to present quantitative works on growth and remodelling (G&R) processes in the reproductive system to understand normal tissue mechanical function and to determine mechanisms of tissue pathologies. Tissues within the reproductive system drastically adapt their structure and mechanical properties in response to biochemical and biomechanical stimuli through a person’s lifespan. The underlying mechanisms by which these processes occur and how they differ in healthy and pathological states, however, remain to be elucidated. Thus, the purpose of this session is to showcase techniques to quantify tissue grow and remodelling in normal and pathological conditions in reproductive health including, but not limited to, pregnancy, the uterus and placenta, menopause, gynecologic diseases, pelvic floor disorders, and breast feeding.

Growth and remodelling

Chairs: Salvatore Federico, The University of Calgary, Canada

Chiara Bellini, Northeastern University, USA

Growth and remodelling are the two components of the anelastic process of reorganisation of biological tissue internal structure in response to external stimuli. Topics include, but are not limited to, the differential geometric, multi-scale, computational and biological aspects of the process of growth-remodelling.

Image-based multiscale modeling of soft tissues

Chair: Manuel Rausch, The University of Texas, USA

 

 

Soft tissues are ubiquitous and play vital roles in our bodies. These tissues are hierarchical structures and, for a detailed understanding of their function, require a multiscale modeling approach. This session will bring together a group of presenters who use an image-based approach to understanding these tissues, their functions, and their roles in disease.

Imaging and image analysis for biomechanics

Chair: Philip Bayly, Washington University in St. Louis, USA

Advanced imaging and image analysis methods have emerged as powerful tools for the study of mechanics in general, and biomechanics in particular. Non-invasive, high-resolution, and fast imaging techniques, from optical, to ultrasound and MRI, allow measurement of complex structures, motion, and mechanical properties across many length scales. This symposium will showcase recent work in which novel imaging and image analysis methods has uncovered or elucidated important features of the mechanical behavior of cells and tissues.

Imaging Approaches and Models in Bone Biomechanics

Chairs: Jeffry Stephen Nyman, Columbia University, USA

X. Edward Guo, Columbia University, USA

Combining knowledge about the mechanical behavior of bone with advanced imaging techniques of tissues has the potential to improve our ability to identify patients who are at risk of a fragility fracture as well as the cause of their poor fracture resistance. This session will disseminate the latest advances in the assessment of the mechanical behavior of bone. Topics will cover multiple disciplines such as magnetic resonance imaging that provides structural and compositional properties of bone, non-linear finite element models that incorporate the ability of bone to resist damage accumulation and crack growth, novel image processing techniques that quantify key micro-structural/architectural properties of bone adaptation, and new insights into factors that promote or hinder the fracture resistance of bone.

Injury Biomechanics and Crash Analysis

Chairs: Lyndia Wu and Peter Cripton, University of British

Columbia, Canada

This session will survey state-of-the-art research on impact biomechanics and injury biomechanics that investigate the mechanisms of how physical trauma leads to tissue damage and physiological dysfunction, and how this knowledge may improve prevention, diagnostics, and treatment. Topics will range from experimental and imaging methods to characterize tissue tolerance and measure real-world or simulated injury cases, to modeling and computational methods that analyze injury biomechanics and predict injury risks.

Integrating Neuromusculoskeletal Modeling with Rehabilitation Robotics


Chairs:   Mohammad S. Shourijeh, Rice University, USA

              B.J. Fregly, Rice University, USA

 

The goals of this scientific session are to:

1) bring together experts in the fields of neuromusculoskeletal modeling and rehabilitation robotics 

2) motivate more neuromusculoskeletal modelers to work on applications related to rehabilitation

 

3) discuss the current status of technology in both fields towards the use of neuromusculoskeletal modeling in the design and improvement of rehab robots

In vivo imaging and visualization

Chair: Lucas H. Timmins, University of Utah, USA

Recent advances in medical imaging technologies now provide non-invasive methods to evaluate tissue anatomy and function, interrogate the biomechanical environment, and promote clinical diagnostic and prognostic strategies. However, these imaging advances require complementary advances in scientific visualization strategies to process, interpret, and interact with these data. This session will highlight the unique convergence of innovations in medical imaging and scientific visualization towards establishing disruptive technologies to advance biomedical research and clinical medicine. 

Micro-physiological Systems or Organ-on-Chip

Chairs: David Elad, Tel Aviv University, Israel

Ben Maoz, Tel Aviv University, Israel

Micro-Physiological Systems (MPS) and Organ on a Chip (OoC) are new in vitro platforms designed for studying human physiology. This concept emulate the in vivo spatial, chemical, structural, and physiological elements of tissue and organ, using human cells in a microfluidic cell culture chip. This allows to study organ-organ interactions and disease states. 

Ocular biomechanics

Chair: Ross Ethier, Georgia Institute of technology and Emory University

School of Medicine, USA

Jonathan Vande Geest, University of Pittsburg, USA

Biomechanics plays an important role in ocular function and pathophysiology, including conditions such as glaucoma, myopia, keratoconus and trauma. Direct experimental measurements of the ocular biomechanical environment are often difficult or impossible, and thus computational modeling is critical to understanding basic biological and physiological processes in the eye, at the cellular and whole tissue levels. The goal of this session is to present state-of-the-art research in this exciting area.

Société de Biomécanique Session: Joint imaging and musculosketal modelling

Chair: Raphael Dumas, Université de Lyon – IFSTTAR, France

 

 

Subject-specific data are used more and more frequently in musculoskeletal models to increase their bio-fidelity and their relevance for clinical applications. Muscle and bone geometries are derived from medical imaging, but joint range of motion, degrees of freedom, alignment, and contact locations mostly remain generic. This session will focus on joint imaging (e.g. CT-scan, MRI, EOS, and fluoroscopy) and its use for developing and/or validating subject-specific musculoskeletal models.

Soft tissue damage, strength and fracture

Chair: Edoardo Mazza, ETH Zürich, Switzerland

Anne Robertson, University of Pittsburg, USA

 

 

Next to deformation behavior, modeling and prediction of deterioration and rupture of soft biological tissue represent key challenges for the analysis of medical problems. This session will discuss current knowledge about mechanisms determining damage, strength and fracture of soft biological tissues, the formulation of corresponding models and the associated computer methods. 

Soft tissue mechanics, damage, and remodelling 

Chair: Grace O'Connell, University of California, Berkeley, USA

This session will highlight approaches to modeling damage in soft tissue.  Particular emphasis will be placed on experimental methods used to develop damage criteria.

Soft tissues and hydrogels biomechanics 1

Chairs: Dominique Pioletti, EPFL, Switzerland

Sam Evans, Cardiff University, UK

Soft tissues and hydrogels biomechanics 2

Chairs: Martyn Nash, The University of Auckland, New Zealand

Cees Oomens, TUE Eindhoven, Netherlands

 

 

Soft tissues and hydrogel biomechanics - topic include:
- development of theoretical, experimental and numerical methods for analysing biomechanics of soft tissues and hydrogels.
- application of mathematical and computational modelling techniques to study biomechanics of hydrogels and soft tissues (e.g. heart, skin, skeletal muscle, pelvic floor, breast, tendon, brain, lung, stomach, liver, cartilage, etc), and in the context of clinical, translational and pathophysiological problems.
- new advancements for measurement, characterisation and identification of
biomechanical parameters of soft tissues and hydrogels.

Sports biomechanics using in-game full-body 3D tracking of player

Chairs: António Veloso, University of Lisbon, Portugal 

Scott Selbie, TUE Eindhoven, Director of Research at C-Motion & Acting CEO at Theia Markerless Inc.

The common theme of the four presentations is the recording of full-body 3D motion of athletes during a live performance. Recent advances in computer vision, machine learning, and graphical processing units (GPUs) have made possible the development of human motion tracking algorithms that function in indoor and outdoor environments without the need of subject cooperation or body worn sensors. This session will address examples from Baseball, Track and Field and Football, in which elite athletes were tested in live game situations or during regular training sessions guaranteeing competitive and natural behaviour.

Symposium in honor of Professor Christopher Jacobs: Chris Jacobs' students and fellows session

Chairs: Ron Kwon, University of Washington, USA

Alesha Castillo, New York University, USA

This session will highlight the scientific legacy of Prof. Jacobs by showcasing research from his students and fellows. In the spirit of Dr. Jacobs' enthusiasm for multidisciplinary approaches, this session will focus on emerging biological systems that address key questions in skeletal development, regeneration, and mechanotransduction. 

Symposium in honor of Professor Christopher Jacobs: Computational biomechanics

Chairs: Ellen Kuhl, Standford University, USA

Scott Delp, Standford University, USA

Symposium in honor of Professor Christopher Jacobs: Musculoskeletal mechanobiology

Chairs: Farsh Guilak, Washington University, USA

Hank Donahue, Virginia Commonwealth University, USA

Thrombosis modeling

Chairs: Danny Bluestein, Stony Brook University, USA

Kevin Moerman, NUI Galway, Ireland

The coagulation cascade of blood may be initiated by flow-induced platelet activation and aggregation and/or interaction of the blood constituents with a vascular wall in which the endothelium is impaired. This, in turn, may prompt thrombus formation and potential embolization characterizing vascular disease processes, as well as thrombus and thromboemboli formation in prosthetic cardiovascular devices. The session will put an emphasis on advanced simulation approaches that incorporate blood flow with the multiscale/multiphase nature of thrombosis, as well as their experimental validation.

Urinary track and reproductive biomechanics session

Chairs: Sara Roccabianca, Michigan State University, USA

Kristin Myers, Columbia University, USA

Biomechanics plays a key role in the function of organs in the lower abdomen. In recent years it has become apparent that many dysfunctions of both the lower urinary tract and the reproductive system are heavily influenced by the microstructural remodeling of the soft tissues that compose these systems. This session will showcase the state-of-the-art research that aims to increased understanding of the forces that drive mal-adaptation in the lower abdomen. This exciting research area has the potential to transform the way we think about pathologies in the lower abdomen, from preterm birth to pelvic organ prolapses to neurogenic urinary dysfunction.

Vascular mechanics

Chair: Chiara Bellini, Northeastern University, USA

Salvatore Federico, The University of Calgary, Canada

The session aims at exploring theoretical and computational aspects of the mechanics of the vasculature in health and disease. Topics include, but are not limited to, in-vivo and in-vitro characterization of the vasculature, constitutive modeling of vascular tissues, predictive models of vascular mechanics during development, aging, and disease progression, incorporation of imaging data in computational models of the vasculature.